According to the study published in the European Journal of Endocrinology, the obese person is subjected to be at higher risk of COVID-19 severity and death than any other normal body mass index (BMI).
The study also suggested that a BMI of more than 30 had shown the connection with a significantly higher risk of admission to intensive care, respiratory failure, and death in COVID-19 patients, regardless of gender, age, and other associated illness. In the UK, the present guidelines set for identifying the high-risk people are with a BMI of more than 40. However, the present study suggests that a person with more than 30 BMI should be considered at a higher risk.
Obesity is growing, and the novel pandemic is linked to a variety of diseases and an increased risk of death. Since the beginning of the coronavirus outbreak, a number of findings have suggested obesity as a risk factor for many adverse effects and death in Sars-COV-2 infection.
The UK and the US have set a BMI of 40 and above as the guidelines to identify the patients who are at higher risk. But these testimonials were necessarily based on limited data and smaller studies, providing the novelty and fast progression of the Sars-COV-2 pandemic.
Italy-based University of Bologna, the Alma Mater Studiorum’s Dr. Matteo Rottoli, and colleagues had conducted a study on almost 500 patients and analyze the outcome of the hospitalized COVID-19 patients. They found that obesity was linked with a notably higher risk of severity and death and that any BMI of more than 30 was linked with these adverse outcomes.
Dr. Rottoli comments, their findings have shown that any grade of obesity is having a connection with adverse COVID-19 illness and suggested that people with mild obesity should also be classified as a population at risk.
There is a strong connection between higher BMI and severe COVID-19 illness, but it is yet to be explained. A damaged immunological response to alterations of viral infections, lung function, and obesity-related chronic inflammatory states have all been suggested as the link. The next step of this research would be to understand these mechanisms.
Their hypothesis is that Sars-CoV-2 infection results depend on the metabolic profile of patients and that obesity, interlock with metabolic syndrome, and diabetes are involved too, Dr. Rottoli added.
Dr. Rottoli warned that the BMI cut-off should be reevaluated to ensure that researchers identify every individual at a higher risk of severe infection and avoid underestimating the potential population impact of SARS-CoV-2 infection, specifically in Western countries with higher obesity rates.
Dr. Rottoli recommends that health-care practitioners and people should be aware of the increased risk of COVID-19 illness with any grade of obesity.
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