A new study suggests that male coronavirus survivors contain a high level of antibodies in their blood that fights viruses effectively than women. So doctors are asking men who are recovered from coronavirus to donate plasma to treat sick patients in trials.
As a possible treatment for coronavirus, Convalescent plasma is being trialled all around the globe. The plasma contains the antibodies developed from the coronavirus recovered people's immune system.
The UK-based non-departmental public body, NHS Blood and Transplant, requested donors and stated that the center has studied and found that male donors have high antibody levels in their plasma than female donors. Male donors have almost 43-29% more antibodies than females due to the male tendency to becoming sicker than females.
NHS Blood and Transplant associate director for blood donation Prof David Roberts said, initially, an individual's immune system would try and battle with a coronavirus with white blood cells (WBC). If an individual becomes more sick, his/her immune system must develop more antibodies to kill or neutralize the virus's effectiveness. Our findings and many other studies around the world have suggested that men with coronavirus infection are possibly more to become seriously ill than women. This makes male better plasma donors once they have recovered.
In the UK, 2 of the major trials are underway. The Oxford-based Recovery trial is undergoing a number of treatments, including convalescent plasma. The testing of plasma has already shown that it has a widely available steroid, dexamethasone, curb the death rate in the sickest patients. The positive patients recovered of all ages in Recovery trial are eligible for convalescent plasma from the time of admitting to the hospital.
A second smaller trial titled Remap-Cap trial is providing convalescent plasma to adults in the intensive care unit.
The University of Cambridge intensive care doctor, Prof David Menon, said that there has always been an enormous global interest in the convalescent plasma's potential. To rapidly deliver a result from the trials, it is really very essential to get plasma from donors with high antibody levels. So the transfusion of plasma has the best chance of influencing the clinical course and results of the disease.
Convalescent plasma has also been used to treat other diseases like Ebola.
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